I gave the 1st one to my dog, 1st of this month. However, they are possible, so it is better to know they might happen. She has been itching uncontrollably since I gave her the simparica. I gave it to her then I looked at the box that said never tested on pregnant dogs . I don't want another animal harmed by this stuff, one animal is one to many. I had to put him laundry room for the night (no Carpet). We may also give additional medications to keep fleas, ticks, and common intestinal parasites away. We have a 3 month old Aussie labradoodle and the breeder warned against oral flea meds. It is the most convenient flea and tick protection product on the market. Nothing stopped the seizures and our Pickles passed away after just a few months of symptoms. Bella is a very anxious dog and is my husbands shadow. best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. The cost of Simparica Trio generally ranges from $2230 per dose depending on the tablet size, number of doses, and source of purchase. All said, we are over $8K into vet bills and growing, Given that he had no noted medical issues prior, his vet and the urgent care vet both feel is was likely the Simparico. (Ours never did, she died 4 months later.) Today, he wouldn't eat or drink any water. Hello to everyone and I am so sorry we had to meet under these circumstances. He was given fluids, anti-nausea meds, meds to assist with the inflammation of his esophagus. Our boy Axel had been on Heartgard his entire life. I'm also wondering if his anxiety is related as well. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. I could never forgive myself. I just wanted to get another opinion before we move forward. (145 Reviews) $15.50 - $31.09. He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. So you can imagine my worry now. She continued to have seizures even she was on phenobarbital. PROS Treats adult fleas and prevents flea and tick infestations Effective against five types of tick Liver flavored tablet FDA Approved CONS I bought chicken last night he ate some of that . My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! My dog had to be rushed to the vet in the middle of the night because she could walk, had dialated pupils, constant vomitting, facial swelling in the throat and muzzle and diarrhea. And urinating more often as a result. Hoping that these side effects dont get worse and subside soon . What Are The Side Effects Of Simparica Trio For Dogs? She was shaking like she was freezing. Snores like a big dog. We are now back to regular vet with bloodwork every two weeks and still on meds and diarrhea but not as bad. Hope all is well. I will be discontinuing the medication. No more of this med! I took her home. It definitely can cross blood brain barrier and cause other neurological issues so it makes sense it could do this too, but clearly they havent done enough research to understand how. I called the manufacturer (Zoetis) and filed a report, immediately discontinued the tablets and started to detox him. Animal Drug Safety Communication: FDA Alerts Pet Owners and Veterinarians About Potential for Neurologic Adverse Events Associated with Certain Flea and Tick Products, How to Report Problems with Flea and Tick Products, An official website of the United States government, : What are the side effects of Simparica Trio Chewable Tablets for Dogs? Then they come back! I won't sleep until we all get the justice for our babies that don't have voices of their own. He started having skin issues that the vet said were allergic reactions probably due to environmental things. My poor baby! It is the flea and tick component that is the problem. old . Mine was given the medication 9 days ago. Moxidectin stops heartworm . We had family in for the weekend and he was not himself. Simparica Trio works to prevent heartworm disease, treat and prevent flea infestations, treat and control tick infestations, and treat and control roundworms and hookworms. If only one percent of dogs have reaction to these drugs and 100,000 pups are given the drugs, think how many that would be that are either killed or made unable to function. With the March 1 dose, on that day, I noticed him seeming to be very fearful and flinching on several occasions. Hes not well..we hope he recovers fully! I will be speaking to vet to switch to something else. We contacted the company using the phone number supplied in the under in the box and shared our experience with the new drug. He had an MRI and it came out good. I dont like that my dog looks at me like he doesnt know who I am. I have been giving my lab puppy (6 months old now) Simparica Trio since October. Update on my Labradoodle who started seizures just a few hours after receiving first dose of Simparica on T-Day 2020 it is March 2021 and my Vet put my dog on Phenobarbital for anti-seizure med. Stressing out now. I have already had a bad experience with "k9 advantix", so I refuse to buy over the counter drugs for my 13 week old Auggie. I wish I had seen this post first. Was checking out before using . Advised her to put a big note on our account that she is never to have this again. Our miniature schnauzer has been extremely thirsty and itchy to the point of biting until he bleeds. We wont be using this medicine ever again! Not sure what effects he will continue to have. I am worried! Any believers out there please say a prayer for our pup as I will for the people on this thread. He's been in an emergency hospital for two nights, no signs of improvement despite blood transfusions and other symptoms. She's pacing and wants to eat grass. Monday morning - 11 days after he is like a zombie - all motions are almost mechanical and when I talk to him it takes him a long while to react. Also I read on Dr Mercola site that heartworms is in the dogs blood not the digestive track and garlic won't work. Insurance for dogs, cats, and other household animals can run as low as $20 a month, but that cost can add up over time. Used my own intuition and knowledge to make a good choice for my pet .good luck to everyone one here ! Vet says Simparica is not the reason for his condition, but he was totally fine prior to taking Simparica!! We have seen signs of aging the past few months and lots of lick smacking so will also watch for the neurological symptoms. After the ER visit and a visit with our regular vet today, they concluded he is having neurological issues and that is why he cannot walk. She is more worried about excessive thirst, lip smacking and her kidneys. We just gave the first does to our 11 week old Sheepadoodle puppy yesterday. Sarah thanks for your response! It hurts to see this and infuriating to know these stories are out here and we did not do the research before giving our little guys this poison. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. Do you have a homeopathic vet in your area? I should have know it was a sign when he spat it out. I feel like this drug was pushed by my vet tech and veterinarian. Gave this to my dogs and now he sleeps all the time and tired and has symptoms now like droopy right side weakness cant blink right eye and drooling like bells palsy. My dog is still having tremors 5 months after taking Simparica. Our two shih tzus are 6.5. My vet seems skeptical that this is related to simparica but it seems clear to me, although I realize that anecdotal cases don't prove it. Got a new GS when the old one died. Hard fast shaking and terrified eyes. She was riddled with parasites when she was found as a stray, and then treated for heartworm disease just before I adopted her. Sarolanerstarts fighting fleas within three hours and begins to kill ticks after 8 hoursincluding the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. I will have to keep an eye out on her. Best case scenario, he is able to come home, but we aren't there yet. She was being seen by her regular vet and was put on antibiotics. After 9 days he began vomitting, even water, and mouth chattering like he was scared. Two quick questionsDo the dogs eventually return to normal? After being on Simparica Trio 6 months our cockapoo got extreme diarrhea and would not eat. I finally got him to eat some chicken and he threw that up 2 hours later. I paid $120 for 6 months of poison. But the wandering and "head pressing" it's called, where they just go into the corner or lean against a table leg or the wall. Started in February and within a couple of weeks ears started twitching. This content shouldnt take the place of advice by your vet. Has odd agitated swallowing when not eating anything. Thank you all so much!!!! She is still eating but she is drinking more water. Things like: Bloody Diarrhea In a margin of safety study, Simparica was administered orally to 8-week old Beagle puppies at doses of 0, 1, 3, and 5 times the maximum exposure dose of 4 mg/kg at 28-day intervals for 10 doses. I gave this for the first time to my hound and about 3 hours later, she was very unsteady on her feet, eyes half shut and then had 4 episodes of breathing rapidly that each lasted 30 seconds or so and all happened within a 30 minute period. Today shes acting better, finally, but her back legs are still collapsing and she is weak. Once she is completely healed I am putting her back on those. She is still in the vet since 3am. 4.3 4.3 out of 5 stars (34,534) $39.98 $ 39. I looked up side effects for this drug and was horrified to find that the flea med can cause tremors seizures and worse. UPDATE We had one normal day on Friday. Any suggestion? Can my dog still get Lyme disease from a tick that was in him. A couple of weeks later she had lost weight from not eating. Please anyone let me know if there is a class action law suit or where we can start one? Now, here we are one month later and I just gave him the second dose about two hours ago. He has horrible water like stools. My American Akita puppy took this pill on August 8th. She is scared of her own shadow, walks into things at times, trips and stumbles, has become very timid, stares at the wall and has to have either me or my husband in sight at all times. Back to the vet and I hope they credit my money. Will not use this again and will warn others. His motor skills have been affected and hes been losing weight even though he eats heartily. Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. It has been 5 days since she had the 3 seizures in 24 hours. 5 hours after the dose she's home resting. Twice I have seen his eyes roll into the back of his head (petti-mal seizure?) 38 results for "simparica trio for dogs" RESULTS. Today is day three and she is a little better, with fewer episodes of tremor and more often able to walk without falling. I gave my 10 year old Bull Terrier a dose of Simparico Trio Thursday December 3. We are already close to $2000 in Vet bills not counting the poison we bought her. My Labradoodle had extreme diarrhea last night. My dog has been on simpatico trio for 5 months .. and still got a deer tick .. Decreased conscious proprioception. We hope this will solve our problems and he can live a healthy and happy life. Thank you all so much for this thread and giving me hope. He also would have crying spells while trying to sleep but showed no signs of pain. I gave my 15 year old dog this medicine. I'm so scared. I am SO angry with my vet and so mad at myself for not researching first. All is good! Just after the 4th dose he started to collapse at his feeding dishes on the floor, next we raised dishes and he did ok for being shaky but continued to decline to the point where he could not use dishes , and now cant eat or drink. Sold as 1 Month, 3 Month or 6 Month Supply for the following dog weights : 2.8-5.5 lbs, 5.5-11 lbs, 11-22 lbs, 22-44 lbs, 44-88 lbs, 88-132 lbs. She seems to be feeling better but still very concerned of why these levels are still up. We go for more bloodwork today and are praying for better news. and to only let him out on a leash to go potty. Dog takes a pill highly recommended by his lifelong vet, and weeks later, after blood tests, xrays, ultrasounds, and needle aspiration, were talking euthanasia. How can you give a dog a pesticide to ingest. Simparica Trio can be administered to your dog at any age, but it's best to start treating your dog one month before the fleas become active. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. Billy Boy is a 9 week old Daisy Dog. I have an appointment this Wednesday but not sure if Im going to keep it if the cough will go away eventually. its been 2 weeks .We just had a blood draw done again and they are still high. Then he starts scratching and as time goes on he seemed like something was wrong. I just gave Bentlee my Akita Simparica Trio on the 9th. If undiagnosed he would have died. I put him on boiled chicken & rice and got him calmed down. 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